Publications

Members of the ACCP sometimes publish on behalf of the ACCP in the interests of education and knowledge sharing on many topics related to, but not necessarily exclusively on, Comparative Haematology and Biochemistry. Previous examples of ACCP publications include the Journal of Comparative Clinical Pathology (now in it's 25th year) and a Haematology Atlas (now in its 2nd edition). In addition, other publications are occasionally produced by members such as  Animal Haematotoxicology: A Practical Guide for Toxicologists and Biomedical Researchers, and Animal Clinical Chemistry: A Primer for Toxicologists. These publications are commercially available and are excellent resources.

Comparative Clinical Pathology

Main editor: Paul Sibbons. Publisher: Springer-Verlag

Comparative Clinical Pathology (previously Comparative Haematology International) provides a source for the publication of reviews, research reports, technical notes and case histories covering all aspects of Haematology and Clinical Chemistry in any species.

 

The journal addresses itself to all scientists with an interest in the field of comparative clinical pathology: research institutes, toxicology and pathology laboratories, medical and veterinary colleges and practices, zoological institutes, universities and teaching hospitals. 

 

Comparative Clinical Pathology publishes papers encompassing the total spectrum
of comparative

clinical pathology including: classical Haematology and Clinical Chemistry, cellular and organ physiology and function, Toxicology, Immunology, cell kinetics, Haemostasis, Haematopoietic and other malignancies, immunodeficiency states, Molecular Biology, immunophenotyping, bone marrow transplantation, enzymology, endocrinology, cytokines, haematopoietic growth factors, evolutionary medicine, cellular lineage, rheology, functional identification and biomarkers.

 

Articles can incorporate: normal values, abnormal reactions, human, veterinary and zoological data, diagnostic and toxicological changes, experimental studies (both in vivo and in vitro) and new technology and its impact on diagnosis and disease control.

Atlas of Comparative Diagnostic and Experimental Hematology

2nd Edition 

Authors: Smith CA & Jarecki A. Publisher: Wiley-Blackwell

A vital resource on blood and bone marrow cell morphology in laboratory animal medicine. This fully revised new edition is an essential reference for clinical pathologists in diagnostic laboratories, and medical or veterinary research. The atlas contains over 400 colour images of cells from the peripheral blood and bone marrow from a variety of animals encountered in laboratory animal medicine, in health and disease.

 

Key features: New chapter on flow cytometry and its application in terms of routine analyses as a means of identifying abnormalities in cell marker

expression, which is of particular relevance for
pre-clinical safety assessment.

 

Covers the most recent developments in laboratory animal Haematology, including parameters measured by the latest generation of analysers.

 

Coverage includes a wide range of laboratory animal species, as well as those used in clinical veterinary trials.

 

Photomicrographs present normal and abnormal blood cells from a variety of hematological conditions along with descriptive text.

Animal Haematotoxicology: A Practical Guide for Toxicologists
and Biomedical Researchers

Author: G. O. Evans.CRC Press; 2009

This book is designed to help new entrants to the fields of laboratory animal haematology and toxicology, where the challenges are stimulating and the 'rules' for human haematology do not always apply. 

 

There are many good general textbooks on human haematology and toxicology, with each organisation having it's favourites: This book is aimed to bridge the gap between these two main stream sciences.

 

Chapters are written to cover the three main blood cell types - erythrocytes, leukocytes, and thrombocytes - and potential toxic effects on these cells.

A chapter on immunotoxicology has been included

as this scientific discipline is closely aligned to haematology. 

 

Other chapters are devoted to preanalytical and analytical variables that affect animal studies, as these play a far more important part when interpreting data in contrast to humans, where many of these variables can be well controlled or have less physiological effect.

 

Information has been collated from published papers, textbooks, and unpublished data: references are provided at the end of each chapter or in Appendix A, where readers are provided with some key references on published reference ranges for laboratory animals.

Animal Clinical Chemistry: A Primer for Toxicologists

Author: G. O. Evans. CRC Press; 2009

Newcomers to the animal clinical chemistry and toxicology fields quickly find that the same rules of human medicine do not always apply.

 

Following in the footsteps of its standard-setting first edition, Animal Clinical Chemistry: A Practical Handbook for Toxicologists and Biomedical Researchers, Second Edition collates information widely dispersed in journals and book chapters, focusing on the most relevant literature to experimental toxicology and its distinction from human medicine.

 

This tome expands discussion of Troponins, Lipids, and Electrolytes. In addition to tests recommended by regulatory authorities, this globally relevant resource includes information about clinical chemistry tests as well as hepato-, nephro-, cardio-, and endocrine toxicity. It also covers pre-analytical and analytical variables, which play a far more important role

with interpreting data from animal studies as compared to human studies when variables can be well controlled with less physiological effect. Furthermore, this edition takes its discussion of biomarkers to the next level, exploring newer and related investigations, such as metabolomics/NMR and multiplex technology.

 

Under the editorial guidance of G.O. Evans, a recognized field authority, the book presents background information on the selection and application of biochemical tests in preclinical safety assessment studies. It also assesses specific organ toxicity, such as in the liver, kidney, and thyroid, along with regulatory requirements and statistical approaches. Careful to avoid delving into overly complex detail, this text is a comprehensive, practical reference ideal for new entrants to the field. However, its broad scope and depth also make it suitable for more seasoned scientists and Toxicologists.